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What is pemphigus? Symptoms? When to suspect?

What is pemphigoid?

Pemphigoid is a rare autoimmune disorder that can develop at any age, including in kids, but that most often affects the elderly. Pemphigoid is caused by a malfunction of the immune system and results in skin rashes and blistering on the legs, arms, and abdomen.

What is epidermolysis bullosa?

Epidermolysis bullosa is a rare condition that causes fragile, blistering skin. The blisters may appear in response to minor injury, even from heat, rubbing or scratching. In severe cases, the blisters may occur inside the body, such as the lining of the mouth or stomach.

What causes these diseases?

These are autoimmune disorders that happens when the immune system attacks healthy skin. Immune molecules called antibodies target proteins called desmogleins, which help link neighboring skin cells to one another. When these connections are broken, skin becomes fragile and fluid can collect between layers of cells, forming blisters.

Can any medicines cause these diseases?

Some drugs that cause this condition include antibiotics and blood pressure medication. Blisters can develop months after taking the medicine.

Whom to consult for such diseases?

If your primary healthcare provider can’t diagnose you, you may have to see a specialist like a gastroenterologist or a rheumatologist.

Is it contagious?

No,you can't catch them from other people. Autoimmune diseases do tend to run in families, which means that certain genes may make some people more likely to develop a problem.

What investigations need to be done?

laboratory tests used to diagnose autoimmune disorders often depend on the particular disorder suspected. Blood tests that indicate the presence of inflammation are usually performed to help diagnose an autoimmune disorder. When autoimmune disease is suspected, the common laboratory evaluation will serve as an initial red flag to pursue further testing.

Is there any effective treatment? How long?

There are no cures for autoimmune diseases, but symptoms can be managed. Everyone’s immune system, genetics and environment are different. That means that your treatment must be unique.

Is hospitalization required?

Autoimmune patients, in particular, can find themselves needing the hospital as there is a wide variety of symptoms possible.

Is it life threatening?

For most people, the disease can be controlled with treatment.Pemphigus is a potentially life-threatening autoimmune blistering disease. However, little is known about the all-cause and cause-specific mortality among patients with pemphigus compared with the general population

Is it permanently curable?

There are no cures for autoimmune diseases, but symptoms can be managed. Everyone's immune system, genetics and environment are different. That means that your treatment must be unique.

How to take care of the wounds?

Gently cleanse the wound with mild soap and lukewarm water and pat it dry. Apply a sterile bandage. Increase your protein intake to speed tissue repair. Ask your rheumatologist whether you need more aggressive treatment of your underlying autoimmune disease to get systemic inflammation under control.

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